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LGD-4033/MK-677 Ingredient Identification, Purity, and Concentration. / R28866

Prepared for:
Olympus Labs UK 
www.olympuslabs.uk
April 16, 2023 

Client & Sample Information

Client: Olympus Labs UK
www.olympuslabs.uk
Study:
LGD-4033/MK-677 Ingredient Identification, Purity, and Concentration
Task Number: #28866
Batch Number: OL2211
Verification Key: 6NYY7C9NMEPI – Verify

Summary

Raw Material: MK-677 | Molecular Formula: C27H36N4O5S
Molecular Weight: 528.662 CAS No.: 159752-10-0
Raw Material: LGD-4033 Molecular Formula: C14H12F6N2O
Molecular Weight: 338.25 CAS No.: 1165910-22-4

Purity:

The raw materials of LGD-4033/MK-677 powder were tested by HPLC-MS for purity.  Based on the HPLC chromatographic purity measurement, LGD-4033 was tested to be >99.99% pure and MK-677 was calculated to be greater than 99% pure using the area normalization method.

Concentration:

A bottle labeled “LGD-4033/MK-677” with the batch number “OL2211” was received on 14 April 2023. The powder inside the capsule was assayed for the concentrations of the intended active ingredients using HPLC-DAD. The total concentration of LGD-4033 was 5.40mg and the total concentration of MK-677 found was 9.66mg.

Purity:

A bottle labeled “LGD-4033/MK-677” with the batch number “OL2211” was received on 14 April 2023. Analysis was conducted on the contents of the capsule by extraction of the active compounds using GC-MS under a blind screening method developed to detect common anabolic steroids and aromatase inhibitors by Janoshik. LGD-4033 and MK-677 were both positively identified.

Raw Material Purity Test Results

Raw Material Identification & Concentration Test Results

Results & Discussion

Bottle labeled LGD-4033/MK-677 with batch number OL2211 was positively identified for LGD-4033 and MK-677 with a concentration of 5.40 mg per capsule of LGD-4033 and 9.66 mg of MK-677 with MK-677 having an assay of >99% purity and LGD-4033 having an assay of >99.99% purity.
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